Soft Tissue Sarcoma Treatment

Soft tissue sarcoma treatment in Israel is performed by specialists of the Oncology Department at Herzliya Medical Center in Israel. Excellent results have been achieved using modern and highly efficient methods of diagnosis and treatment, making it world-famous. Herzliya Medical Center (HMC) in Israel, the country's leading oncologists specialize in treating all types of cancer, such as the treatment of sarcomas, including soft tissue sarcomas. Modern equipment allows HMC to treat patients using the most technologically advanced cancer treatments.

Soft Tissue Sarcoma

Sarcomas are malignant tumors that originate from connective tissue cells that make up all internal organs, forming the basis of muscle, fat, blood vessels, tendons and sheaths of nerve fibers. Sarcomas may be responsible for some aggressive cancers and are often characterized by having the capacity to be highly invasive with respect to surrounding tissues. . Apart from its ability to spread, these malignant neoplasms are also characterized by early hematogenous metastasis (blood). Soft tissue sarcomas can occur in patients of all age groups. Risk factors for this type of cancer are genetic mutations (Li-Fraumeni syndrome, Gardner's syndrome, Werner syndrome), the presence of precancerous lesions (basal cell nevus, neurofibromatosis), and influence of carcinogenic factors, including radiation.

Soft Tissue Sarcomas Types

There are several types of soft tissue sarcomas, including:

  • Rhabdomyosarcoma - sarcoma that develops from striated skeletal muscle fibers
  • Leiomyosarcoma (LMS) - smooth muscle tumor found primarily in organs of the gastrointestinal tract
  • Hemangiosarcoma – an aggressive, rapidly growing sarcoma that develops in the blood vessels, often in areas exposed to ionizing radiation
  • Lymphangiosarcoma - a tumor that develops in the blood vessels of the lymphatic system
  • Kaposi's sarcoma - malignant degeneration of connective tissue cells in the walls of blood vessels, characteristic of patients with acquired immunodeficiency syndromes
  • Synovial sarcoma - tumor localized in the synovial membranes of the joints
  • Neurofibrosarcoma - a tumor that affects the connective tissue structures of the peripheral nerves
  • Liposarcoma - characterized by a primary malignant transformation of adipose tissue
  • Fibrosarcoma (malignant fibrous histiocytoma) - tumors of fibrous tissue, mainly affecting the lower limbs
  • Dermatofibrosarcoma - fibrous tissue that affects deeper layers of the skin

Soft Tissue Sarcoma Symptoms

Clinical signs of soft tissue sarcoma depend on the location and sized of the primary tumor, and the presence of secondary metastatic lesions. The rapid growth of sarcoma leads to significant local destruction accompanied by severe pain, dysfunction of internal organs, and bleeding. Patients experience general weakness, fever, progressive weight loss, and secondary anemia as the disease progresses. Large abdominal tumors are often caused by acute intestinal obstruction and require emergency surgery. Sarcomas of the chest can cause severe respiratory and hemodynamic disturbances.

Soft Tissue Sarcoma Diagnosis

After thorough physical examination by experts of Herzliya Medical Center in Israel, risk of having malignant disease is determined, in addition to any additional research required.. Soft Tissue Sarcoma Diagnosis in Israel includes the following methods:

  • Ultrasound examination of soft tissue is of great diagnostic value in determining malignancy. Modern methods of ultrasound can not only diagnose Kaposi duration, but may also control the process of minimally invasive aspiration biopsy.
  • Using X-ray methods of investigation are include intravenous and internal use of contrast material.
  • Tomographic diagnostics determine size, location, and metabolic activity using modern computer techniques, as well as magnetic resonance imaging and positron emission tomography.
  • Biopsy with a full histological analysis, as well as resulting formulation allows determination of a definitive diagnosis regarding sensitivity of a tumor to different treatments.
  • Laboratory studies of the functioning of the internal organs.

Treatment of Soft Tissue Sarcoma

At HMC in Israel, experts have successfully applied modern methods for treatment of soft tissue sarcomas, among them:

  • Surgical treatment is committed to the removal of both primary and metastatic foci of soft tissue sarcoma tumors. The widespread use of neoadjuvant (preoperative) chemotherapy is involved in ablative surgery to remove tumors of the extremities, while maintaining high levels of a successful prognosis
  • Radiotherapy in the treatment of soft tissue sarcomas is part of a comprehensive protocol to significantly increase efficiency of surgeries and conservative therapy
  • Chemotherapy is important both in combination with surgery or as the primary method of cancer treatment in Israel for inoperable forms of sarcoma. Along with the highly traditional methods of cancer treatment, sarcoma Oncologists at HMC in Israel use modern drug-targeted therapy - Imatinib (Gleevec). Targeted therapy for soft tissue sarcoma has an effect on specific metabolic processes of cancer cells highly active in metastatic and recurrent forms of the disease
  • Rehabilitation therapy is undergone after removal of soft tissue sarcoma. Postoperative rehabilitation programs help patients quickly recover any loss in functioning and have the choice of convenient, easy to use esthetic dentures

For many years, Herzliya Medical Center in Israel has been the leading multi-disciplinary hospital specializing in cancer treatment. The vast experience of highly-qualified staff takes an individual approach in the treatment of malignant neoplasms. Treatment is provided in the best conditions in the country and at an unsurpassable level of service quality.


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